REVIEW ARTICLE
ADVANCES IN THE USE OF STEM CELLS THERAPY IN VETERINARY CLINICAL PRACTICE
Z. A. Bhutta1*, M. F. A. Kulyar2*, A. Kanwal3, W. Yao2,4, R. Ahmed5, S. Shabbir6, M. Asif7, S. Nawaz8, M. Ali9, M. Shoaib10, A. S. Rukh11, H. J. Arshad12and R. Hussain13
1Laboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea
2College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, PR China
3Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, 63100, Pakistan
4Department of Microbiology and Plant Pathology, University of California-Riverside, Riverside, CA, 92521, USA
5Public Health Pests Laboratory, Jeddah Municipality, Jeddah, Kingdom of Saudi Arabia
6Graduate School of Chinese Academy of Agricultural Science, Beijing 100081, P. R. China
7Department of Surgery, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan
8Department of Pathology, University of Agriculture, Faisalabad, 38000, Pakistan
9Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, 38000, Pakistan
10Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs/ Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, 730050 Lanzhou, PR China
11Department of Pharmaceutical Sciences, Superior University, Lahore, Pakistan
12Center of Agricultural Biochemistry and Biotechnology, University of Agriculture, Faisalabad, 38000, Pakistan
13Department of Pathology, Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, 63100, Pakistan
*Corresponding author’s email: doctorzeeshan94@gmail.com , fakharealam786@hotmail.com
ABSTRACT
Stem cells are self-organized, unspecialized cells which are produced from various types of cells in all tissues of the body. They can be derived through a proper methodology from embryos, fetus and adults. Stem cells can divide into specific cell types, such as nerves or muscles. These cells are a source of information about cell differentiation processes and tissue homeostasis, but they are also one of the main biological tools for treating degenerative diseases. In the past 20 years, researchers have paid great attention to stem cell biology. Therefore, an understanding of its characteristics has greatly enhanced regarding to its therapeutic potential in all aspects in past few years. Role of stem cells is important for veterinary medicine in various ways. Several stem cell treatments for animals are currently being developed, such as treatment of equine tendinopathies disease through mesenchymal stem cells. In addition, animal models are widely being used to study the properties of stem cells and their potential in human medicine. These cells are now being artificially grown and transformed into special types of cell cultures that are compatible with cells from different tissues. This paper summarizes the current knowledge of stem cells potential in veterinary medicine.
Keywords: animal, regenerative medicine, stem cell therapy, stem cells, veterinary |